yl9193永利导师简介-刘晓
来源:yl9193永利
作者:
发布时间:2022-06-16
所属学科名称:中药化学
导师简介: 刘晓
个人简介:
刘晓,1987年11月生,生药学博士,毕业于中国医学科学院、北京协和医学院药物研究所,现为永利官网副研究员,2019.8-2021.1赴美国德克萨斯大学奥斯汀分校Hung-wen Liu group进行公派访学。目前已在Nat. Chem. Biol., J. Am. Chem. Soc., Org. Lett., J. Nat. Prod., Adv. Synth. Catal., Acta. Pharm. Sin. B, RSC Adv., Bioorg. Med. Chem. Lett., Fitoterapia, 中国中药杂志, 药学学报,中草药等国内外知名期刊发表学术论文100余篇,获得专利授权5项,承担国家级课题3项,省部级课题2项,校级课题2项。获教育部自然科学奖二等奖一次,入选第四届中国科协青年人才托举工程,入选永利官网杰出青年人才(优青培育)项目及青年科学家培育计划(科研新锐人才),任中华中医药学会中药化学分会青年委员。主要研究方向为中药活性成分合成生物学研究。
主要研究方向:
1. 中药活性成分合成生物学研究;
2. 中药材中具新颖催化活性次级代谢酶的发现及催化分子机制研究
科研成果(不多于350字):
1) 科研项目:
国家自然科学基金面上项目 (Grant No. 82173922);
国家自然科学基金青年项目 (Grant No. 81402809);
中国科协青年人才托举项目 (Grant No. CACM-2018-QNRC1-02);
北京市自然科学基金项目 (Grant No. 7192112);
永利官网杰出青年人才项目 (Grant No. 2018-JYB-XJQ006);
天然药物及仿生药物国家重点实验室开放课题 (Grant No. K202119);
2) 代表论著
1. Yaru Yan#, Ting Mo#, Wenqian Huang, Xiping Xu, Weisheng Tian, Yingxia Wang, Yuelin Song, Jun Li, Shepo Shi*, Xiao Liu*, Pengfei Tu*. Journal of Natural Products. 2022, 85(7):1826−1836.
2. Ridao Chen#, Bingquan Gao#, Xiao Liu#, Feiying Ruan, Yong Zhang, Jizhong Lou, Keping Feng, Carsten Wunsch, Shu-Ming Li, Jungui Dai*, Fei Sun*. Nature Chemical Biology. 2017, 13(2): 226–234. (Co-first author)
3. Wenqian Huang#, Yingxia Wang#, Weisheng Tian#, Xiaoxue Cui, Pengfei Tu, Jun Li, Shepo Shi*, Xiao Liu*. Antibiotics. 2022, 11(10):1380.
4. Yu-Hsuan Lee, Xueli Hou, Ridao Chen, Jianqiang Feng, Xiao Liu, Mark W. Ruszczycky, Jin-Ming Gao,* Binju Wang,* Jiahai Zhou,* and Hung-wen Liu*. Journal of the American Chemical Society, 2022, 144(10): 4478–4486.
5. Xiao Liu, Dan Xie, Ridao Chen, Mei Mei, Jianhua Zou, Xiaoguang Chen, Jungui Dai*. Organic Letters, 2012, 14(16): 4106–4109.
6. Ting Mo#, Xiao Liu#*, Yuyu Liu, Xiaohui Wang, Le Zhang, Juan Wang, Zhongxiu Zhang, Shepo Shi*, Pengfei Tu*. RSC Advances, 2016, 6(88): 84616–84626. (Co-first author)
7. Yuyu Liu, Xiaohui Wang, Ting Mo, Yaru Yan, Yuelin Song, Yunfang Zhao, Jun Li, Shepo Shi, Xiao Liu*, Pengfei Tu*. RSC Advances, 2017, 7: 21028–21035. (Co-corresponding author)
8. Xiao Liu, Ridao Chen, Dan Xie, Mei Mei, Jianhua Zou, Xiaoguang Chen, Jungui Dai*. Tetrahedron, 2012, 68(47): 9539–9549.
9. Bowen Qi#, Xiao Liu#, Ting Mo, Zhixiang Zhu, Jun Li, Juan Wang, Xiaoping Shi, Kewu Zeng, Xiaohui Wang, Pengfei Tu, Ikuro Abe, Shepo Shi*. Fitoterapia, 2017, 123: 35–43. (Co-first author)
10. Xiao Liu*, Yaru Yan, Yuyu Liu, Ting Mo, Xiaohui Wang, Yuelin Song, Qingliang Chen, Yunfang Zhao, Shepo Shi*, Pengfei Tu*. Plant Cell, Tissue and Organ Culture, 2018, 134(1), 107–118.
11. Yaru Yan, Bowen Qi, Ting Mo, Xiaohui Wang, Juan Wang, Shepo Shi*, Xiao Liu*, Pengfei Tu*. Chinese Journal of Organic Chemistry, 2018, 38, 2281–2295. (Co-corresponding author)
12. Ridao Chen, Xiao Liu; Jianhua Zou; Yunze Yin, Bin Ou, Jianhua Li, Ruishan Wang, Dan Xie, Peicheng Zhang, JunguiDai*. Advanced Synthesis & Catalysis, 2013, 355(9): 1817–1828.
3) 专利授权
- 糖基转移酶CtGT-I、其编码基因和衍生物及用途,已授权,中国,授权专利号:ZL 2017 1 1454429.8,授权公告日:2020-11-06,排名1/10;
- 制备丙二酰基产物的方法,已授权,中国,授权专利号:ZL 2017 1 1454456.5,授权公告日:2020-09-18,排名2/10;
- III型聚酮合酶及其编码基因和用途,已授权,中国,授权专利号:ZL 2016 1 0037246.5,授权公告日:2019-10-15,排名6/11;
- 一种诱导白木香愈伤细胞产生2-(2-苯乙基)色酮类成分的方法,已授权,中国,授权专利号:ZL 2016 1 0076673.4,授权公告日:2020-09-11,排名6/11
联系方式:fcliuxiao@163.com,liuxiao@bucm.edu.cn